Group A
| Rank | Teams | Played | Won | Drawn | Lost | Differential | Goal difference | Points | Current form |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
 LASK |
6 | 5 | 1 | 0 | 12 - 1 | 11 | 16 | WWWLW |
| 2 |
 Maccabi Tel Aviv |
6 | 3 | 2 | 1 | 14 - 4 | 10 | 11 | WLDLD |
| 3 |
 HJK Helsinki |
6 | 2 | 0 | 4 | 5 - 15 | -10 | 6 | WLLWL |
| 4 |
 Alashkert |
6 | 0 | 1 | 5 | 4 - 15 | -11 | 1 | LLLLD |
Group B
| Rank | Teams | Played | Won | Drawn | Lost | Differential | Goal difference | Points | Current form |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
 Gent |
6 | 4 | 1 | 1 | 6 - 2 | 4 | 13 | DLWLL |
| 2 |
 Partizan |
6 | 2 | 2 | 2 | 6 - 4 | 2 | 8 | DWWLL |
| 3 |
 Anorthosis Famagusta |
6 | 1 | 3 | 2 | 6 - 9 | -3 | 6 | LDDWD |
| 4 |
 FC Flora Tallin |
6 | 1 | 2 | 3 | 5 - 8 | -3 | 5 | LDDWL |
Group C
| Rank | Teams | Played | Won | Drawn | Lost | Differential | Goal difference | Points | Current form |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
 Roma |
6 | 4 | 1 | 1 | 18 - 11 | 7 | 13 | LWDWW |
| 2 |
 Bodø/Glimt |
6 | 3 | 3 | 0 | 14 - 5 | 9 | 12 | WWDWL |
| 3 |
 Zorya Luhansk |
6 | 2 | 1 | 3 | 5 - 11 | -6 | 7 | LWWLD |
| 4 |
 CSKA Sofia |
6 | 0 | 1 | 5 | 3 - 13 | -10 | 1 | DLLLL |
Group D
| Rank | Teams | Played | Won | Drawn | Lost | Differential | Goal difference | Points | Current form |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
 AZ |
6 | 4 | 2 | 0 | 8 - 3 | 5 | 14 | WDWLD |
| 2 |
 Randers |
6 | 1 | 4 | 1 | 9 - 9 | 0 | 7 | DWLLL |
| 3 |
 Jablonec |
6 | 1 | 3 | 2 | 6 - 8 | -2 | 6 | LDDDL |
| 4 |
 CFR Cluj |
6 | 1 | 1 | 4 | 4 - 7 | -3 | 4 | DLLLW |
Group E
| Rank | Teams | Played | Won | Drawn | Lost | Differential | Goal difference | Points | Current form |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
 Feyenoord |
6 | 4 | 2 | 0 | 11 - 6 | 5 | 14 | DWWDL |
| 2 |
 Slavia Praha |
6 | 2 | 2 | 2 | 8 - 7 | 1 | 8 | WWLDL |
| 3 |
 Union Berlin |
6 | 2 | 1 | 3 | 8 - 9 | -1 | 7 | WLLWD |
| 4 |
 Maccabi Haifa |
6 | 1 | 1 | 4 | 2 - 7 | -5 | 4 | LWLLL |
Group F
| Rank | Teams | Played | Won | Drawn | Lost | Differential | Goal difference | Points | Current form |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
 København |
6 | 5 | 0 | 1 | 15 - 5 | 10 | 15 | WWWDL |
| 2 |
 PAOK |
6 | 3 | 2 | 1 | 8 - 4 | 4 | 11 | WWWLL |
| 3 |
 Slovan Bratislava |
6 | 2 | 2 | 2 | 8 - 7 | 1 | 8 | DWWDL |
| 4 |
 Lincoln Red Imps |
6 | 0 | 0 | 6 | 2 - 17 | -15 | 0 | LLLLL |
Group G
| Rank | Teams | Played | Won | Drawn | Lost | Differential | Goal difference | Points | Current form |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
 Rennes |
6 | 4 | 2 | 0 | 13 - 7 | 6 | 14 | WDWLW |
| 2 |
 Vitesse |
6 | 3 | 1 | 2 | 12 - 9 | 3 | 10 | WLWLD |
| 3 |
 Tottenham |
6 | 2 | 1 | 3 | 11 - 11 | 0 | 7 | WLWLL |
| 4 |
 NŠ Mura |
6 | 1 | 0 | 5 | 5 - 14 | -9 | 3 | LLLWL |
Group H
| Rank | Teams | Played | Won | Drawn | Lost | Differential | Goal difference | Points | Current form |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
 Basel |
6 | 4 | 2 | 0 | 14 - 6 | 8 | 14 | DWWLL |
| 2 |
 Qarabağ |
6 | 3 | 2 | 1 | 10 - 8 | 2 | 11 | WDLLL |
| 3 |
 Omonia |
6 | 0 | 4 | 2 | 5 - 10 | -5 | 4 | LLDDD |
| 4 |
 Kairat |
6 | 0 | 2 | 4 | 6 - 11 | -5 | 2 | LLLLD |
Knockout
Preliminary knockout round
1/16 Final
Thursday 17 February, 2022 12:45
1/8 Final
1/4 Final
1/2 Final
Final
Data by Statorium soccer API